Description

Piperidine, 1-[[4-[[4-(2-Benzothiazolyl)-1-Piperidinyl]Sulfonyl]Phenyl]Sulfonyl]-3,5-Dimethyl- (9Ci) is a specialized, high-value piperidine derivative featuring a benzothiazole core and multiple sulfonyl linkages, making it a critical advanced pharmaceutical intermediate for targeted drug discovery. This compound is essential for research and development in medicinal chemistry, particularly for creating novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, functionalized piperidine-benzothiazole scaffold.
• Protease Inhibitor Development: Serves as a core structural motif in the design and development of protease inhibitors, leveraging the sulfonyl groups for binding interactions.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.
• High-Throughput Screening Libraries: Incorporated into diverse compound libraries for screening against novel biological targets to identify potential hits.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs) in clinical trials.

Basic Information

Product Name	Piperidine, 1-[[4-[[4-(2-Benzothiazolyl)-1-Piperidinyl]Sulfonyl]Phenyl]Sulfonyl]-3,5-Dimethyl- (9Ci)
CAS No.	606083-03-8
Molecular Formula	C25H29N3O4S3
Molecular Weight	531.71 g/mol
Synonyms	1-[[4-[[4-(2-Benzothiazolyl)-1-piperidinyl]sulfonyl]phenyl]sulfonyl]-3,5-dimethylpiperidine; 3,5-Dimethyl-1-({4-[(4-{1,3-benzothiazol-2-yl}piperidin-1-yl)sulfonyl]phenyl}sulfonyl)piperidine; 1-({4-[(4-{1,3-Benzothiazol-2-yl}piperidin-1-yl)sulfonyl]phenyl}sulfonyl)-3,5-dimethylpiperidine; UNII-7Q3K6T4K0F; 7Q3K6T4K0F; 1-[[4-[[4-(2-benzothiazolyl)-1-piperidinyl]sulfonyl]phenyl]sulfonyl]-3,5-dimethyl-piperidine
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing results from HPLC, NMR, and mass spectrometry. We support cGMP-compliant manufacturing for advanced pharmaceutical applications, with documentation tailored to meet regulatory requirements for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.