Description

Pyridine, 2-Ethoxy-5-(Trifluoromethyl)- is a specialized fluorinated pyridine derivative, identified by CAS No. 605681-37-6, valued for its unique trifluoromethyl and ethoxy substituents which confer distinct electronic and steric properties. This compound serves as a critical high-value building block in advanced organic synthesis, particularly for creating complex molecules with tailored functionality. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the stability of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Precursor for organic electronic materials and liquid crystals, where its fluorine content modifies electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	Pyridine, 2-Ethoxy-5-(Trifluoromethyl)-
CAS No.	605681-37-6
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-Ethoxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-ethoxypyridine; 2-Ethoxy-5-trifluoromethylpyridine; 2-Ethoxy-α,α,α-trifluoro-p-picoline
EINECS	Contact for details

Quality Control

Our Pyridine, 2-Ethoxy-5-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical property classification, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.