Description

1-(5-Bromo-Pyridin-3-Yl)-Propan-2-One is a high-purity brominated pyridine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its reactive ketone and halogenated aromatic structure, enabling the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bromopyridine moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Scale-Up: A fundamental building block for contract research organizations (CROs) and CDMOs offering custom synthesis services from milligram to kilogram scale.

Basic Information

Product Name	1-(5-Bromo-Pyridin-3-Yl)-Propan-2-One
CAS No.	605681-06-9
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)-2-propanone; 2-Propanone, 1-(5-bromo-3-pyridinyl)-; 5-Bromo-3-acetonylpyridine; 3-Acetonyl-5-bromopyridine; 1-(5-Bromopyridin-3-yl)propan-2-one; 5-Bromo-3-pyridylacetone; 1-(5-Brom-3-pyridyl)-propan-2-on (German); 1-(5-Bromo-3-pyridyl)-2-propanone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-Pyridin-3-Yl)-Propan-2-One is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.