Description

Spiro[Cyclohexane-1,2-Furo[3,4-D][1,3]Dioxol]-4-Ol, Tetrahydro-, (3As,4S,6As)- (9Ci) is a complex spirocyclic compound featuring fused dioxolane and tetrahydrofuran rings, serving as a sophisticated chiral building block and intermediate in advanced organic synthesis. Its unique, rigid three-dimensional structure is critical for imparting specific stereochemical and conformational properties in target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where precise spatial orientation is required for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and antiviral compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its spirocyclic core contributes to enhanced efficacy and environmental profile.
• Asymmetric Catalysis: Employed as a precursor or ligand component in the development of chiral catalysts for stereoselective chemical transformations.
• Material Science Research: Serves as a building block for novel organic frameworks and functional materials with specific optical or electronic properties.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance ingredients and other high-value specialty chemicals.

Basic Information

Product Name	Spiro[Cyclohexane-1,2-Furo[3,4-D][1,3]Dioxol]-4-Ol, Tetrahydro-, (3As,4S,6As)- (9Ci)
CAS No.	604789-22-2
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	(3aS,4S,6aS)-Tetrahydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4-ol; Tetrahydrospiro[cyclohexane-1,2-furo[3,4-d][1,3]dioxol]-4-ol, (3aS,4S,6aS)-; Spiro[cyclohexane-1,2-furo[3,4-d][1,3]dioxol]-4-ol, tetrahydro-, (3aS,4S,6aS)-; (3aS,4S,6aS)-4-Hydroxytetrahydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxole]; CAS 604789-22-2; Spirocyclic dioxolane-furan derivative; Chiral spirocyclic alcohol intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral HPLC to confirm enantiomeric purity and NMR for structural verification. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment. We support development and scale-up projects with custom purity grades and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.