Description

Piperazine, 1-[(8-Fluoro-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) is a sophisticated heterocyclic compound that serves as a critical building block in advanced organic synthesis. This high-purity intermediate is valued for its unique molecular architecture, which combines a piperazine ring with a fluorinated quinoline moiety. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of potential APIs, leveraging its fluorinated quinoline structure for bioactivity modulation.
• Biochemical Research: Employed as a reference standard or a building block in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of complex, high-value agrochemicals or performance chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for client-specific molecules.

Basic Information

Product Name	Piperazine, 1-[(8-Fluoro-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci)
CAS No.	604773-25-3
Molecular Formula	C14H14FN3O2
Molecular Weight	275.28 g/mol
Synonyms	1-[(8-Fluoro-4-hydroxy-3-quinolinyl)carbonyl]piperazine; 8-Fluoro-4-hydroxy-N-(piperazin-1-yl)quinoline-3-carboxamide; (8-Fluoro-4-hydroxyquinoline-3-carbonyl)piperazine; Piperazine, 1-[(8-fluoro-4-hydroxy-3-quinolinyl)carbonyl]-; Quinoline-3-carboxamide, 8-fluoro-4-hydroxy-N-1-piperazinyl-; CAS 604773-25-3
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[(8-Fluoro-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.