Description

2-Pyridinepropanoicacid,α-Amino-5-Methyl-,Ethylester(9Ci) is a specialized pyridine derivative that serves as a crucial chiral building block and intermediate in advanced organic synthesis. Its value lies in its structural complexity, which enables the construction of sophisticated molecules with high stereochemical control. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, particularly in exploring new C-N and C-C bond-forming reactions.
• Peptidomimetic Scaffolds: Its α-amino ester functionality makes it suitable for constructing non-natural amino acid analogs and peptidomimetics in drug discovery.

Basic Information

Product Name	2-Pyridinepropanoicacid,α-Amino-5-Methyl-,Ethylester(9Ci)
CAS No.	603945-37-5
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	Ethyl 2-Amino-3-(5-methylpyridin-2-yl)propanoate; α-Amino-5-methyl-2-pyridinepropanoic Acid Ethyl Ester; 2-Pyridinepropanoic acid, α-amino-5-methyl-, ethyl ester; 5-Methyl-DL-phenylalanine ethyl ester (pyridine analog); Ethyl 2-amino-3-(5-methyl-2-pyridyl)propionate; 3-(5-Methylpyridin-2-yl)-L-alanine ethyl ester; (RS)-2-Amino-3-(5-methyl-2-pyridyl)propionic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of our 2-Pyridinepropanoicacid,α-Amino-5-Methyl-,Ethylester(9Ci) undergoes rigorous analytical testing to ensure identity, purity, and consistency. We employ advanced techniques including HPLC, GC, and NMR to verify specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with each shipment, supporting compliance in GMP-oriented synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.