Description

Lithium 3-Fluoropyridine-2-Carboxylate is a high-purity organolithium reagent and a key fluorinated heterocyclic building block. This compound is essential for introducing the 3-fluoro-2-pyridinecarboxylate moiety into complex molecular architectures, enabling precise structural modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used to construct fluorinated pyridine cores in the development of new-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and fluorinated liquid crystals.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Lithium 3-Fluoropyridine-2-Carboxylate
CAS No.	603310-20-9
Molecular Formula	C6H3FNO2Li
Molecular Weight	147.04 g/mol
Synonyms	3-Fluoropyridine-2-carboxylic acid lithium salt; 2-Pyridinecarboxylic acid, 3-fluoro-, lithium salt; Lithium 3-fluoro-2-pyridinecarboxylate; 3-Fluoro-2-pyridinecarboxylic acid lithium salt; 3-Fluoropicolinic acid lithium salt; Li-3-Fluoropicolinate
EINECS	Contact for details

Quality Control

Our Lithium 3-Fluoropyridine-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all relevant specifications. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.