Description

Cyclopropanecarboxamide, N-[5-(3-Pyridinyl)-1,3,4-thiadiazol-2-yl]- (9CI) is a high-purity, heterocyclic organic compound featuring a cyclopropane carboxamide core linked to a pyridinyl-thiadiazole moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors. The compound is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for critical synthesis applications.

Application

This specialized chemical serves as a key synthetic precursor in several high-value research and development areas:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Agrochemical Development: Intermediate in the research and synthesis of new active ingredients for crop protection.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and target engagement.
• Organic Synthesis Reference Standard: Used as a pure standard for analytical method development and validation in QC laboratories.

Basic Information

Product Name	Cyclopropanecarboxamide, N-[5-(3-Pyridinyl)-1,3,4-thiadiazol-2-yl]- (9CI)
CAS No.	603073-23-0
Molecular Formula	C11H9N5OS
Molecular Weight	259.28 g/mol
Synonyms	N-(5-(Pyridin-3-yl)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide; 3-Pyridinyl-1,3,4-thiadiazole-2-cyclopropanecarboxamide; Cyclopropanecarboxylic acid [5-(3-pyridyl)-1,3,4-thiadiazol-2-yl]amide; 603073-23-0; UNII-9F6P0F2W8K; 9CI Cyclopropanecarboxamide derivative; 2-Cyclopropanecarboxamido-5-(3-pyridyl)-1,3,4-thiadiazole
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxamide, N-[5-(3-Pyridinyl)-1,3,4-thiadiazol-2-yl]- (9CI) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure it meets the exacting standards required for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation or clumping. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.