Description

8-Oxa-5-Azaspiro[3.5]Nonane is a high-value, heterocyclic spiro compound featuring a unique bridged structure that serves as a critical building block in advanced organic synthesis. Its rigid, three-dimensional framework is essential for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This versatile intermediate is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides and insecticides, leveraging its spirocyclic scaffold.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chelating ligands and organocatalysts.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic frameworks with specific physical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	8-Oxa-5-Azaspiro[3.5]Nonane
CAS No.	602326-48-7
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	5-Aza-8-oxaspiro[3.5]nonane; 8-Oxa-5-azaspiro[3.5]nonane; Oxa-azaspiro[3.5]nonane; Spiro[3.5]nonane, 8-oxa-5-aza-; 1-Oxa-4-azaspiro[4.4]nonane (alternative numbering); Tetrahydro-1,4-oxazepine, hexahydro derivative
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production of 8-Oxa-5-Azaspiro[3.5]Nonane adheres to current Good Manufacturing Practices (cGMP) where applicable. Every batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.