Description

1-Azabicyclo[2.2.2]octane,3-isocyano-(9Ci) is a specialized bicyclic organic compound featuring a reactive isocyanide functional group. This unique structure makes it a versatile and high-value building block in advanced organic synthesis, particularly for constructing complex nitrogen-containing heterocycles. It is primarily sought after by pharmaceutical researchers and fine chemical manufacturers for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those with quinuclidine or related bicyclic amine scaffolds.
• Ligand Synthesis: Used to create specialized isocyanide ligands for organometallic chemistry and catalysis.
• Multicomponent Reaction (MCR) Chemistry: Serves as a critical reactant in Passerini and Ugi-type reactions to rapidly generate molecular diversity libraries.
• Agrochemical Research: Employed in the development of novel herbicides and insecticides with specific biological activity.
• Material Science: Utilized in the synthesis of functional polymers and advanced organic materials.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry at research institutions.

Basic Information

Product Name	1-Azabicyclo[2.2.2]octane,3-isocyano-(9Ci)
CAS No.	602268-99-5
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	3-Isocyanoquinuclidine; Quinuclidin-3-yl isocyanide; 1-Azabicyclo[2.2.2]octane-3-carbonitrile, 3-isocyano-; 3-Isocyanoquinuclidine; 1-Azabicyclo[2.2.2]oct-3-yl isocyanide; 3-Quinuclidyl isocyanide; 1-Azabicyclo[2.2.2]octane, 3-isocyano-
EINECS	Contact for details

Quality Control

Our production of 1-Azabicyclo[2.2.2]octane,3-isocyano-(9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles. We support custom synthesis and purity requirements to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive nature of the isocyanide group, minimize exposure to air and moisture for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.