Description

1-(2-Isocyano-Ethyl)-4-Methyl-Piperazine is a versatile organic building block featuring both an isocyano and a piperazine functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing novel heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactivity to create complex molecular scaffolds.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry.
• Polymer Modification: Employed to introduce reactive isocyanate or amine functionalities into polymer backbones for advanced material science applications.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and other tools for studying biological systems.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	1-(2-Isocyano-Ethyl)-4-Methyl-Piperazine
CAS No.	602267-60-7
Molecular Formula	C8H15N3
Molecular Weight	153.23 g/mol
Synonyms	4-Methyl-1-(2-isocyanoethyl)piperazine; 1-(2-Isocyanoethyl)-4-methylpiperazine; 2-(4-Methylpiperazin-1-yl)ethyl isocyanide; 4-Methylpiperazine-1-ethyl isocyanide; N-(Isocyanatoethyl)-N'-methylpiperazine (common misnomer); 602267-60-7; 1-(2-Isocyano-Ethyl)-4-Methyl-Piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Isocyano-Ethyl)-4-Methyl-Piperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.