Description

2-(4-Chlorophenyl)Ethylisocyanide is a specialized organic building block featuring an isocyanide functional group attached to a chlorinated aromatic core. This compound matters for its unique reactivity, serving as a versatile precursor in the synthesis of heterocycles and complex molecular frameworks. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients. The compound, with CAS number 602262-89-5, is a key intermediate for advanced medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of heterocyclic compounds with potential biological activity.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, leveraging its aromatic chlorophenyl group for bioactivity.
• Material Science: Serves as a monomer or precursor in the development of specialized polymers and functional materials.
• Chemical Synthesis: Employed in multi-component reactions (MCRs) like the Ugi and Passerini reactions to efficiently create complex amides and other derivatives.
• Ligand Synthesis: Useful for preparing isocyanide-based ligands for catalysis and coordination chemistry.
• Academic & R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-(4-Chlorophenyl)Ethylisocyanide
CAS No.	602262-89-5
Molecular Formula	C9H8ClN
Molecular Weight	165.62 g/mol
Synonyms	1-(Isocyanomethyl)-4-chlorobenzene; 4-Chlorobenzyl isocyanide; (4-Chlorophenyl)methyl isocyanide; 4-Chlorobenzyl isonitrile; p-Chlorobenzyl isocyanide; 2-(4-Chlorophenyl)ethyl isocyanide; 4-Chlorobenzyl Isonitrile; 1-Chloro-4-(isocyanomethyl)benzene
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)Ethylisocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.