Description

2-(2-Methoxyphenyl)Ethylisocyanide is a specialized organic building block featuring an isocyanide functional group attached to a 2-methoxyphenethyl moiety. This compound is valued for its versatility as a key intermediate in multi-component reactions and metal-catalyzed transformations, enabling the efficient synthesis of complex heterocyclic scaffolds. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for constructing nitrogen-containing heterocycles via Ugi, Passerini, and related multicomponent reactions.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its reactivity to create novel pesticidal and herbicidal compounds.
• Ligand Synthesis: Serves as a starting material for the preparation of specialized isocyanide-based ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the creation of activity-based probes and bio-conjugation reagents due to the unique reactivity of the isocyanide group.
• Polymer & Material Science: Utilized in the development of functional polymers and smart materials where the isocyanide group can facilitate specific polymerization or cross-linking reactions.
• Academic & Process R&D: A valuable reagent for methodological development in organic synthesis and for scaling up novel synthetic routes in process chemistry.

Basic Information

Product Name	2-(2-Methoxyphenyl)Ethylisocyanide
CAS No.	602262-85-1
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	1-Isocyano-2-(2-methoxyphenyl)ethane; 2-(2-Methoxyphenyl)ethyl isocyanide; 2-(2-Methoxyphenyl)ethanamine, N-formyl derivative, isocyanide; o-Methoxyphenethyl isocyanide; (2-Methoxyphenethyl)isocyanide; 2-(2-Methoxyphenyl)ethyl isonitrile; 2-(o-Methoxyphenyl)ethyl isocyanide
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Methoxyphenyl)Ethylisocyanide is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard quality commitment includes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.