Description

1-Isocyano-3-Isopropoxypropane is a versatile isocyanide building block used in organic synthesis and pharmaceutical research. This compound matters for its role as a key precursor in multicomponent reactions, enabling the efficient construction of complex heterocyclic scaffolds and natural product analogs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its isocyano group facilitates the creation of new molecular architectures.
• Multicomponent Reaction (MCR) Chemistry: Serves as a key reactant in Passerini and Ugi-type reactions for the rapid generation of chemical diversity and compound libraries.
• Ligand and Catalyst Development: Employed in the preparation of specialized isocyanide-based ligands for metal-catalyzed processes and organocatalysis.
• Polymer Modification: Utilized to introduce functional isocyano groups into polymer backbones for creating materials with tailored properties.
• Academic and Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and discovery chemistry programs.

Basic Information

Product Name	1-Isocyano-3-Isopropoxypropane
CAS No.	602262-07-7
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	3-Isopropoxypropyl isocyanide; 3-Isopropoxypropyl isonitrile; 1-Isocyano-3-isopropoxypropane; Isopropoxypropyl isocyanide; (3-Isopropoxypropyl)isocyanide; NSC 405124; 1-Isocyanato-3-isopropoxypropane (common misnomer); 3-(Isopropoxy)propyl isocyanide
EINECS	Contact for details

Quality Control

Our 1-Isocyano-3-Isopropoxypropane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical characterization, including NMR, GC, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.