Description

Benzene, 4-Chloro-2-Isocyano-1-Methyl- (9Ci) is a specialized aromatic isocyanide derivative, serving as a high-value synthetic intermediate. Its core value lies in its unique reactivity profile, enabling the construction of complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nitrogen-containing heterocycles, such as indoles, quinolines, and imidazoles, which are prevalent in drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its isocyano group for multi-component reactions.
• Ligand Precursor in Catalysis: Serves as a precursor for the preparation of specialized isocyanide-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of functional organic materials and polymers where the isocyano group can act as a versatile handle for polymerization or post-modification.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in isocyanide-based multi-component reactions (IMCRs) like the Ugi and Passerini reactions.

Basic Information

Item	Details
Product Name	Benzene, 4-Chloro-2-Isocyano-1-Methyl- (9Ci)
CAS No.	602262-01-1
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	4-Chloro-2-isocyano-1-methylbenzene; 2-Methyl-5-chlorophenyl isocyanide; 5-Chloro-2-methylphenyl isocyanide; 1-Chloro-4-isocyano-3-methylbenzene; 2-Isocyano-4-chlorotoluene; 4-Chloro-2-methylphenyl isocyanide; 5-Chloro-o-tolyl isocyanide; Benzene, 4-chloro-2-isocyano-1-methyl-
EINECS	Contact for details

Quality Control

Our Benzene, 4-Chloro-2-Isocyano-1-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and other relevant tests are provided to guarantee the material meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.