Description

3-Methylbenzylisocyanide is a versatile organic building block characterized by its reactive isocyanide functional group attached to a methylbenzyl moiety. This compound is of significant value in synthetic organic chemistry, particularly for facilitating the construction of complex heterocyclic and peptidomimetic structures. It is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry, agrochemical research, and materials science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for creating diverse heterocyclic libraries via multicomponent reactions like the Ugi and Passerini reactions.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its structure can be incorporated to modulate biological activity and selectivity.
• Ligand Synthesis in Catalysis: Serves as a starting material for preparing specialized isocyanide-based ligands used in transition metal catalysis for fine chemical synthesis.
• Material Science: Employed in the research and development of functional polymers and advanced organic materials with tailored properties.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules, aiding in the study of biological processes and target identification.

Basic Information

Product Name	3-Methylbenzylisocyanide
CAS No.	602261-96-1
Molecular Formula	C9H9N
Molecular Weight	131.18 g/mol
Synonyms	m-Tolylmethyl isocyanide; (3-Methylphenyl)methyl isocyanide; 3-Methylbenzyl isonitrile; 1-Isocyano-3-methylbenzene; α-Isocyano-m-xylene; m-Methylbenzyl isocyanide; m-Tolylmethyl isonitrile
EINECS	Contact for details

Quality Control

Our 3-Methylbenzylisocyanide is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The product is moisture-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.