Description

2-Methylbenzylisocyanide is a versatile organic building block and reagent, specifically an isocyanide derivative of toluene. This compound matters for its unique reactivity profile, serving as a crucial component in multi-component reactions and as a ligand in organometallic catalysis. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel heterocycles and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the preparation of nitrogen-containing heterocycles via Passerini and Ugi multi-component reactions.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients, including fungicides and herbicides.
• Catalysis & Ligand Chemistry: Acts as a ligand precursor for transition metal catalysts in cross-coupling and other organic transformations.
• Material Science Research: Employed in the synthesis of functional polymers and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in probe development and bioconjugation strategies.
• Academic & Industrial R&D: Serves as a fundamental reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Methylbenzylisocyanide
CAS No.	602261-95-0
Molecular Formula	C9H9N
Molecular Weight	131.18 g/mol
Synonyms	o-Tolylmethyl isocyanide; (2-Methylphenyl)methyl isocyanide; 1-Isocyano-2-methylbenzene; 2-Methylbenzyl isonitrile; α-Isocyano-o-xylene; Benzene, 1-(isocyanomethyl)-2-methyl-; o-Methylbenzyl isocyanide
EINECS	Contact for details

Quality Control

Our 2-Methylbenzylisocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and spectroscopic identification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.