Description

Benzene, 1-Fluoro-2-(Isocyanomethyl)- (9Ci) is a specialized fluorinated aromatic isocyanate building block, identified by CAS number 602261-90-5. This compound is valued for its dual reactive sites, enabling its use as a versatile synthon in advanced organic synthesis and materials science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atom and isocyanate group impart specific biological activity and stability.
• Specialty Polymer & Resin Production: Acts as a monomer or cross-linking agent for creating high-performance polyurethanes, polyisocyanurates, and other polymers with enhanced chemical resistance.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its unique electronic properties from the fluorine substituent.
• Chemical Research & Development: A critical building block in medicinal chemistry and material science research for exploring structure-activity relationships and new material properties.

Basic Information

Product Name	Benzene, 1-Fluoro-2-(Isocyanomethyl)- (9Ci)
CAS No.	602261-90-5
Molecular Formula	C8H4FNO
Molecular Weight	149.12 g/mol
Synonyms	2-Fluoro-α-isocyanotoluene; 1-Fluoro-2-(isocyanomethyl)benzene; 2-Fluorobenzyl isocyanate; α-Isocyanato-2-fluorotoluene; (2-Fluorophenyl)methyl isocyanate; 2-Fluorobenzylisocyanate; 1-Isocyanatomethyl-2-fluorobenzene; 2-Fluoro-1-isocyanatomethylbenzene
EINECS	Contact for details

Quality Control

Every batch of Benzene, 1-Fluoro-2-(Isocyanomethyl)- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support development through to commercial scale, meeting the stringent requirements of research and fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.