Description

4-Bromobenzylisocyanide is a versatile and high-value organic building block characterized by its reactive isocyanide functional group. This compound is essential for facilitating the synthesis of complex heterocyclic and pharmaceutical intermediates through multicomponent reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for lead optimization and novel compound library generation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly for oncology and central nervous system (CNS) targets via multicomponent reactions like the Ugi and Passerini reactions.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides by constructing complex molecular scaffolds.
• Material Science: Used in the preparation of functionalized polymers, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Serves as a valuable tool for bioorthogonal labeling and activity-based protein profiling (ABPP) due to its specific reactivity.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and for creating diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	4-Bromobenzylisocyanide
CAS No.	602261-85-8
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	1-Bromo-4-(isocyanomethyl)benzene; p-Bromobenzyl isocyanide; (4-Bromophenyl)methyl isocyanide; 4-Bromobenzyl isonitrile; Isocyanomethyl-4-bromobenzene; 4-Bromobenzyl Isocyanide; p-Bromobenzyl isonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromobenzylisocyanide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.