Description

3,4-Dioxobutanoic Acid Ethyl Ester is a versatile and reactive keto-ester building block of significant importance in synthetic organic chemistry. Its bifunctional structure, featuring both a reactive 1,2-diketone and an ester group, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is primarily sought by research and development chemists, as well as process development teams in the pharmaceutical, agrochemical, and fine chemical industries, for applications in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of heterocyclic compounds, including pyrroles, furans, and pyrazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create complex molecular architectures.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and specialty polymers requiring specific diketone functionalities.
• Academic & Industrial Research: Employed in methodological studies and as a starting material for developing new synthetic routes and catalysts.
• Coordination Chemistry: Acts as a ligand precursor for metal complexes due to its oxygen-rich, chelating structure.

Basic Information

Product Name	3,4-Dioxobutanoic Acid Ethyl Ester
CAS No.	600160-23-4
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	Ethyl 3,4-dioxobutanoate; Ethyl 2-oxo-3-oxobutanoate; 3,4-Dioxobutyric Acid Ethyl Ester; Acetylpyruvic Acid Ethyl Ester; Ethyl Acetylpyruvate; 1,2-Diacetylethyl Acetate; Butanoic acid, 3,4-dioxo-, ethyl ester; Ethyl 3-oxo-2-oxobutanoate
EINECS	Contact for details

Quality Control

Our 3,4-Dioxobutanoic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. Due to its reactive diketone moiety, prolonged storage should be minimized; use under an inert atmosphere for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.