Description

6-(4-(Trifluoromethyl)Phenyl)Pyridin-3-Amine is a high-purity, specialized aromatic amine building block featuring a trifluoromethylphenyl substituent, a key structural motif valued for its ability to modulate the physicochemical properties of target molecules. This compound is essential for research and development in advanced material science and pharmaceutical chemistry, where its unique electronic and steric profile is leveraged. It is primarily sought by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and structure-activity relationships (SAR).
• Ligand Synthesis for Catalysis: Used to prepare sophisticated nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other organic transformations.

Basic Information

Product Name	6-(4-(Trifluoromethyl)Phenyl)Pyridin-3-Amine
CAS No.	600133-35-5
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	3-Amino-6-[4-(trifluoromethyl)phenyl]pyridine; 6-[4-(Trifluoromethyl)phenyl]-3-pyridinamine; 6-(4-Trifluoromethylphenyl)pyridin-3-amine; 5-Amino-2-(4-trifluoromethylphenyl)pyridine; 2-(4-Trifluoromethylphenyl)-5-aminopyridine; 5-Amino-2-(α,α,α-trifluoro-p-tolyl)pyridine; 3-Pyridinamine, 6-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 6-(4-(Trifluoromethyl)Phenyl)Pyridin-3-Amine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with specifications for residual solvents and related substances available. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support customer-specific quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.