Description

N,1-Bis(Trimethylsilyl)-5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is a specialized organosilicon-protected indole derivative, serving as a crucial advanced intermediate in complex organic syntheses. Its value lies in providing a protected amine and hydroxyl functionality, enabling selective reactions in sensitive pharmaceutical and fine chemical manufacturing processes. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing indole scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring protected functional groups.
• Fine Chemical Production: Serves as a versatile intermediate for creating specialty chemicals, dyes, and pigments.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex nitrogen-containing heterocycles.
• Material Science: Potential precursor in the development of organic semiconductors and advanced polymeric materials.
• Process Chemistry: Employed in scalable manufacturing routes where the trimethylsilyl (TMS) groups provide stability and solubility advantages.

Basic Information

Product Name	N,1-Bis(Trimethylsilyl)-5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine
CAS No.	69937-46-8
Molecular Formula	C21H42N2O2Si3
Molecular Weight	454.82 g/mol
Synonyms	5-[(Trimethylsilyl)oxy]-N,1-bis(trimethylsilyl)-1H-indole-3-ethanamine; 1H-Indole-3-ethanamine, N,1-bis(trimethylsilyl)-5-[(trimethylsilyl)oxy]-; Tris(trimethylsilyl) Protected Tryptamine Derivative; TMS-Tryptamine Derivative; 3-(2-Aminoethyl)-N,1-bis(trimethylsilyl)-5-(trimethylsilyloxy)indole; Protected 5-Hydroxytryptamine Derivative
EINECS	Contact for details

Quality Control

Our N,1-Bis(Trimethylsilyl)-5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.