Description

n-Phenyl-3-[Bis(2-Chloroethyl)Amino]Benzamide is a specialized nitrogen mustard derivative with a benzamide core structure, designed for targeted chemical synthesis and research applications. This compound is valued for its role as a key intermediate in the development of novel bioactive molecules, particularly in medicinal chemistry and pharmaceutical research. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of potential therapeutic agents and advanced chemical libraries.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of nitrogen mustard-based prodrugs and targeted chemotherapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel compounds with alkylating activity for potential cancer therapy.
• Bioconjugation Studies: Serves as a functional handle for attaching cytotoxic payloads to antibodies, peptides, or other targeting molecules in antibody-drug conjugate (ADC) research.
• Chemical Biology Probes: Employed in the development of molecular probes to study DNA alkylation and cellular repair mechanisms.
• Fine Chemical Synthesis: An advanced intermediate for custom synthesis services catering to the agrochemical and specialty materials sectors.
• Academic Research: Utilized in university and institutional labs for investigating the mechanisms and applications of DNA-alkylating agents.

Basic Information

Product Name	n-Phenyl-3-[Bis(2-Chloroethyl)Amino]Benzamide
CAS No.	69884-94-2
Molecular Formula	C19H22Cl2N2O
Molecular Weight	365.30 g/mol
Synonyms	3-[Bis(2-chloroethyl)amino]-N-phenylbenzamide; N-Phenyl-3-[bis(2-chloroethyl)amino]benzamide; Benzamide, N-phenyl-3-[bis(2-chloroethyl)amino]-; 3-(Bis(2-chloroethyl)amino)benzanilide; NSC 176319; U-9889; CB 1954 analog; Nitrogen mustard benzamide derivative
EINECS	Contact for details

Quality Control

Our production of n-Phenyl-3-[Bis(2-Chloroethyl)Amino]Benzamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake. Handle and store in accordance with all applicable local and international regulations for laboratory chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.