Description

3,15α,17β-Tris(Trimethylsiloxy)-1,3,5(10)-Estratriene CAS NO 69833-61-0 is a high-purity, organosilicon-protected derivative of estradiol, designed for advanced synthetic chemistry applications. This compound is valued for its role as a key synthetic intermediate, offering enhanced stability and solubility for precise chemical transformations in controlled environments. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel steroid-based compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D laboratories for exploring new synthetic pathways and studying steroid chemistry.
• Process Chemistry: Employed in the development and scale-up of manufacturing processes for high-value specialty chemicals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying hormone receptor interactions and signaling pathways.

Basic Information

Product Name	3,15α,17β-Tris(Trimethylsiloxy)-1,3,5(10)-Estratriene
CAS No.	69833-61-0
Molecular Formula	C27H48O3Si3
Molecular Weight	504.93 g/mol
Synonyms	3,15α,17β-Tris(trimethylsilyloxy)estra-1,3,5(10)-triene; Estra-1,3,5(10)-triene-3,15α,17β-triol, tris(trimethylsilyl) ether; 3,15α,17β-Tris-O-(trimethylsilyl)estratriene; TMS-Estradiol Derivative; Tris(trimethylsiloxy)estratriene; 69833-61-0; Estratriene tris(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 3,15α,17β-Tris(Trimethylsiloxy)-1,3,5(10)-Estratriene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets exacting specifications for research and synthesis. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.