Description

Norepinephrine Bitartrate CAS NO 69815-49-2 is a high-purity pharmaceutical-grade salt of the endogenous catecholamine neurotransmitter and hormone. This compound is critical for its potent vasoconstrictive and cardiac stimulant properties, serving as a key active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers for the formulation of injectable solutions used in critical care and emergency medicine to treat acute hypotension and cardiac arrest.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for emergency medicine.
• Critical Care Solutions: Manufacture of solutions for intravenous administration to manage severe hypotension, septic shock, and cardiogenic shock.
• Cardiac Resuscitation: Component of advanced cardiac life support (ACLS) protocols to restore blood pressure and cardiac output.
• Research Chemical: Used in biochemical and pharmacological research to study adrenergic receptor function and cardiovascular physiology.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Veterinary Medicine: Application in veterinary critical care for similar vasopressor support in animals.

Basic Information

Product Name	Norepinephrine Bitartrate
CAS No.	69815-49-2
Molecular Formula	C8H11NO3 • C4H6O6
Molecular Weight	319.27 g/mol
Synonyms	Noradrenaline Bitartrate; (R)-4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol bitartrate; Levarterenol Bitartrate; L-Norepinephrine Bitartrate; Arterenol Bitartrate; (R)-(-)-Norepinephrine Bitartrate; 1-(3,4-Dihydroxyphenyl)-2-aminoethanol bitartrate; Noradrenaline Acid Tartrate
EINECS	274-201-1

Quality Control

Our Norepinephrine Bitartrate is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is tested to ensure compliance with relevant pharmacopeial monographs (e.g., USP, EP) for identity, purity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C (59-77°F). This product is hygroscopic (moisture-sensitive) and easily oxidized; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-10.5° to -12.5° (c = 2 in water)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%
Bacterial Endotoxins	< 10.0 EU/mg (for injectable grade)
Microbial Enumeration	Conforms to EP/USP criteria for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.