Description

4H-Furo[3,2-C]Pyran-2(6H)-One, 4-[(Trimethylsilyl)Oxy]- is a specialized organosilicon-protected intermediate of significant value in advanced organic synthesis. This compound matters because its trimethylsilyl (TMS) ether group provides a versatile protecting group for hydroxyl functionalities, enabling complex multi-step syntheses with high selectivity and yield. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic molecules and natural product analogs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing fused furanopyranone scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection, leveraging its unique heterocyclic structure.
• Fine Chemical Production: Serves as a precursor for the manufacture of complex flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological studies in synthetic organic chemistry, especially in reactions involving protected hydroxyl groups.
• Material Science Precursor: Potential use in the development of organic electronic materials or advanced polymers due to its silicon-containing heterocyclic core.

Basic Information

Product Name	4H-Furo[3,2-C]Pyran-2(6H)-One, 4-[(Trimethylsilyl)Oxy]-
CAS No.	69782-89-4
Molecular Formula	C10H14O4Si
Molecular Weight	226.30 g/mol
Synonyms	4-[(Trimethylsilyl)oxy]-4H-furo[3,2-c]pyran-2(6H)-one; 4-(Trimethylsilyloxy)furo[3,2-c]pyran-2(6H)-one; 4H-Furo[3,2-c]pyran-2(6H)-one, 4-(trimethylsilyloxy)-; 4-(TMS-Oxy)-4H-furo[3,2-c]pyran-2(6H)-one; TMS-protected 4-hydroxyfuro[3,2-c]pyran-2(6H)-one; 4-Trimethylsilyloxy-4H-furo[3,2-c]pyran-2-one
EINECS	Contact for details

Quality Control

Our 4H-Furo[3,2-C]Pyran-2(6H)-One, 4-[(Trimethylsilyl)Oxy]- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.