Description

(8α,9β,13α,14β,17α,18β)-21,21-Dimethyl-22α-(Trimethylsiloxy)-29,30-Dinorgammaceran-3-One is a high-purity, steroidal ketone derivative featuring a strategically positioned trimethylsiloxy group. This compound is valued for its role as a critical synthetic intermediate in advanced organic and pharmaceutical chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel therapeutic agents and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial R&D for exploring new chemical transformations and constructing complex molecular frameworks.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialized, high-value chemicals for various industrial applications.
• Biochemical Research: Employed in studies investigating steroidal pathways and receptor interactions due to its modified gammacerane structure.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing production processes for steroidal compounds.

Basic Information

Item	Details
Product Name	(8α,9β,13α,14β,17α,18β)-21,21-Dimethyl-22α-(Trimethylsiloxy)-29,30-Dinorgammaceran-3-One
CAS No.	69774-02-3
Molecular Formula	C33H58O2Si
Molecular Weight	514.90 g/mol
Synonyms	21,21-Dimethyl-22α-(trimethylsiloxy)-29,30-dinorgammaceran-3-one; 22α-(Trimethylsiloxy)-21,21-dimethyl-29,30-dinorgammaceran-3-one; Dinorgammaceran-3-one, 21,21-dimethyl-22α-(trimethylsiloxy)-; TMS-protected gammacerane derivative; Steroidal TMS ether ketone; CAS 69774-02-3
EINECS	Contact for details

Quality Control

Our (8α,9β,13α,14β,17α,18β)-21,21-Dimethyl-22α-(Trimethylsiloxy)-29,30-Dinorgammaceran-3-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.