Description

(8A,9R)- 9-Benzoate- 6'-Methoxy-Cinchonan-9-Ol is a high-purity, chiral alkaloid derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its specific stereochemistry, which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs) with targeted biological activity. This product is essential for research and manufacturing within the pharmaceutical and fine chemical industries, particularly for developers of anti-malarial drugs, chiral catalysts, and other specialized organic syntheses.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex APIs, particularly in anti-malarial drug development.
• Asymmetric Synthesis: Used as a precursor or ligand in the preparation of chiral catalysts for stereoselective chemical reactions.
• Organic Research: Serves as a valuable reference standard and starting material in academic and industrial research focused on cinchona alkaloid chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(8A,9R)- 9-Benzoate- 6'-Methoxy-Cinchonan-9-Ol
CAS No.	69758-70-9
Molecular Formula	C27H28N2O3
Molecular Weight	428.53 g/mol
Synonyms	(8α,9R)-9-Benzoyloxy-6'-methoxycinchonan-9-ol; 9-O-Benzoyl-6'-methoxycinchonan-9-ol; 6'-Methoxycinchonan-9-ol 9-benzoate; Benzoic acid (8α,9R)-9-hydroxy-6'-methoxycinchonan-9-yl ester; A derivative of Cinchonan-9-ol
EINECS	Contact for details

Quality Control

Our (8A,9R)- 9-Benzoate- 6'-Methoxy-Cinchonan-9-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.