Description

Halofantrine is a synthetic phenanthrenemethanol antimalarial agent, identified by CAS NO 69756-53-2. It is a critical pharmaceutical intermediate and active pharmaceutical ingredient (API) valued for its specific activity against certain strains of *Plasmodium falciparum*. This compound is essential for manufacturers and research institutions engaged in the development and production of antimalarial therapeutics and related pharmacological studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antimalarial medications.
• Biomedical Research: Used as a reference standard and investigational compound in parasitology and drug resistance studies.
• Chemical Synthesis: Serves as a key intermediate for the synthesis of novel antimalarial analogs and derivatives.
• Quality Control & Regulatory Compliance: Employed as an analytical standard for HPLC, LC-MS, and other methods to ensure product quality and meet pharmacopeial requirements.

Basic Information

Product Name	Halofantrine
CAS No.	69756-53-2
Molecular Formula	C₂₆H₃₀Cl₂F₃NO
Molecular Weight	500.43 g/mol
Synonyms	Halofantrine Hydrochloride (common salt form); (±)-Halofantrine; 1,3-Dichloro-α-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenanthrenemethanol; SKF-102886; WR-171,669; Phenanthrenemethanol, 1,3-dichloro-α-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our Halofantrine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥98% by HPLC), and impurity profiles is provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The material should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.