Description

16α,17α-Epoxy-1,3,5(10)-Estratriene-3,17β-Diol Diacetate is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its precise molecular structure, which is critical for the synthesis of complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex steroid hormones and related therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) research, and the development of new drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis using techniques like HPLC and GC.
• Process Chemistry: Employed in scale-up and process optimization for the commercial manufacturing of steroid-based APIs.

Basic Information

Item	Details
Product Name	16α,17α-Epoxy-1,3,5(10)-Estratriene-3,17β-Diol Diacetate
CAS No.	69744-63-4
Molecular Formula	C24H30O6
Molecular Weight	414.49 g/mol
Synonyms	16α,17α-Epoxyestradiol Diacetate; 16α,17α-Epoxy-3,17β-estradiol Diacetate; 16α,17α-Epoxyestra-1,3,5(10)-triene-3,17β-diol Diacetate; 3,17β-Diacetoxy-16α,17α-epoxyestra-1,3,5(10)-triene; Estra-1,3,5(10)-triene-3,17β-diol, 16α,17α-epoxy-, diacetate; 16α,17α-Epoxy-3,17β-dihydroxyestra-1,3,5(10)-triene Diacetate
EINECS	Contact for details

Quality Control

Our 16α,17α-Epoxy-1,3,5(10)-Estratriene-3,17β-Diol Diacetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.