Description

(2S)-1-Butyryl-2α-(3-Pyridinyl)Pyrrolidine is a high-purity chiral pyrrolidine derivative, a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a sophisticated intermediate for creating complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical manufacturers focused on neurological and metabolic disorder therapeutics, where precise molecular configuration is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• Neurological Research: Used in the synthesis of compounds targeting nicotinic acetylcholine receptors for potential cognitive and neurological applications.
• Asymmetric Synthesis: Serves as a precursor or catalyst ligand in stereoselective chemical reactions to produce enantiomerically pure substances.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot and commercial production.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	(2S)-1-Butyryl-2α-(3-Pyridinyl)Pyrrolidine
CAS No.	69730-91-2
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	(2S)-1-Butanoyl-2-(3-pyridinyl)pyrrolidine; 1-Butyryl-2-(3-pyridyl)pyrrolidine, (2S)-; (S)-1-Butyryl-2-(3-pyridinyl)pyrrolidine; 2-(3-Pyridinyl)-1-butyrylpyrrolidine, (2S)-; Pyrrolidine, 1-butyryl-2-(3-pyridinyl)-, (2S)-; (S)-2-(Pyridin-3-yl)-1-butyrylpyrrolidine; A-84543 (research code); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2S)-1-Butyryl-2α-(3-Pyridinyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.