Description

(2S)-2α-(3-Pyridinyl)-1-Pyrrolidinecarboxylic Acid Ethyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for the development of complex, biologically active molecules, particularly in pharmaceutical research. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable and high-quality source for constructing novel compounds with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Ligand Synthesis: Serves as a precursor for the preparation of chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of complex specialty chemicals and other high-value intermediates.
• Academic & R&D: A valuable reagent for research institutions and universities conducting studies in medicinal chemistry and synthetic methodology.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(2S)-2α-(3-Pyridinyl)-1-Pyrrolidinecarboxylic Acid Ethyl Ester
CAS No.	69730-90-1
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	Ethyl (2S)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate; (S)-Ethyl 2-(3-pyridyl)pyrrolidine-1-carboxylate; (S)-1-(Ethoxycarbonyl)-2-(3-pyridyl)pyrrolidine; (2S)-2-(3-Pyridinyl)-1-pyrrolidinecarboxylic acid ethyl ester; L-773,022 (historical research code); 1-Pyrrolidinecarboxylic acid, 2-(3-pyridinyl)-, ethyl ester, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2α-(3-Pyridinyl)-1-Pyrrolidinecarboxylic Acid Ethyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC-MS, to verify identity, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.