Description

1-o-[Bis(Trimethylsiloxy)Phosphinyl]-2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Glucopyranuronic Acid Trimethylsilyl Ester is a highly derivatized, silyl-protected carbohydrate intermediate, specifically designed for advanced synthetic organic chemistry. This compound is critical for researchers and manufacturers requiring precise control over glycosylation and phosphorylation reactions in complex molecule assembly. It is primarily utilized in the development of novel pharmaceuticals, sophisticated carbohydrate-based materials, and as a key building block in oligosaccharide synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of nucleoside analogs, antiviral agents, and complex glycoconjugates.
• Oligosaccharide Synthesis: Used in the controlled, stepwise construction of specific oligosaccharide chains for research and therapeutic applications.
• Glycochemistry Research: Acts as a protected precursor for studying glycosylation mechanisms and developing new carbohydrate-based catalysts.
• Prodrug Development: Employed in the design of silyl-protected prodrugs to enhance the bioavailability and stability of active pharmaceutical ingredients (APIs).
• Material Science: Potential use in creating specialized carbohydrate polymers or surface modifiers with unique properties.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories.

Basic Information

Item	Details
Product Name	1-o-[Bis(Trimethylsiloxy)Phosphinyl]-2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Glucopyranuronic Acid Trimethylsilyl Ester
CAS No.	69727-23-7
Molecular Formula	C24H57NO11PSi6
Molecular Weight	Contact for details
Synonyms	D-Glucopyranuronic acid, 1-[bis(trimethylsiloxy)phosphinyl]-2,3,4-tris-O-(trimethylsilyl)-, trimethylsilyl ester; 1-O-[Bis(trimethylsiloxy)phosphoryl]-2,3,4-tri-O-trimethylsilyl-D-glucuronic acid trimethylsilyl ester; Fully silylated D-glucuronic acid phosphate derivative; TMS-Glucuronate phosphate; Per-TMS glucuronyl phosphate; CAS 69727-23-7
EINECS	Contact for details

Quality Control

Our 1-o-[Bis(Trimethylsiloxy)Phosphinyl]-2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Glucopyranuronic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.