Description

4-Hydroxy-4'-Methoxychalcone is a synthetic chalcone derivative, a class of compounds known for their diverse biological activities. This compound serves as a valuable pharmaceutical intermediate and a key scaffold in medicinal chemistry research for developing new therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting inflammation, cancer, and metabolic disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological potency and selectivity.
• Biochemical Research: Serves as a reference standard or inhibitor in enzymatic and cellular assays to study biological pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty chemicals.
• Cosmeceutical Research: Investigated for potential applications in skincare formulations due to the antioxidant properties associated with chalcone structures.

Basic Information

Product Name	4-Hydroxy-4'-Methoxychalcone
CAS No.	69704-15-0
Molecular Formula	C₁₇H₁₆O₃
Molecular Weight	268.31 g/mol
Synonyms	4'-Methoxy-4-hydroxychalcone; (E)-1-(4-Hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one; 4-Hydroxy-4'-methoxy-1,3-diphenyl-2-propen-1-one; 2-Propen-1-one, 1-(4-hydroxyphenyl)-3-(4-methoxyphenyl)-, (E)-; NSC 407296; p-Hydroxy-p'-methoxychalcone; 4,4'-Dihydroxy-3'-methoxychalcone (common misnomer, verify structure).
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-4'-Methoxychalcone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.