Description

Chloroquine Diphosphate CAS NO 69698-56-2 is the diphosphate salt form of chloroquine, a well-established 4-aminoquinoline compound. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of formulated antimalarial and immunomodulatory treatments. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development organizations for the production of bulk drugs, clinical research, and advanced therapeutic studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antimalarial tablet and injectable formulations.
• Clinical Research: Utilized in preclinical and clinical studies for investigating treatments against malaria, autoimmune disorders like lupus and rheumatoid arthritis.
• Bulk Drug Substance: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for secondary manufacturing and global supply chain distribution.
• Reference Standard: Serves as a high-purity chemical standard in analytical laboratories for quality control and method validation.
• Investigational Therapies: Used in research exploring potential antiviral and anticancer applications.

Basic Information

Product Name	Chloroquine Diphosphate
CAS No.	69698-56-2
Molecular Formula	C18H32ClN3O8P2
Molecular Weight	515.86 g/mol
Synonyms	Chloroquine Phosphate; Chloroquine Bis(phosphate); 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline Diphosphate; N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate; Arelan; Aralen Phosphate; Resochin; SN 7618
EINECS	Contact for details

Quality Control

Our Chloroquine Diphosphate is manufactured and tested under a strict quality management system. It is typically produced to meet pharmaceutical-grade specifications, with testing protocols aligned with major pharmacopoeial standards such as USP and EP. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring full traceability and compliance for GMP-driven applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.