Description

Silane, (Estra-1,3,5(10),16-Tetraen-3-Yloxy)Trimethyl- is a specialized organosilicon compound featuring a steroidal estratetraene moiety linked to a trimethylsilyl group via an ether bond. This unique molecular architecture makes it a valuable advanced synthetic intermediate for research and development in pharmaceutical chemistry and materials science. It is primarily sought by R&D chemists and process development scientists working on novel steroid derivatives, silicon-based protecting groups, and high-value fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Chemical Research: Used in academic and industrial R&D for exploring new reaction pathways involving silyl-protected steroid derivatives.
• Advanced Material Synthesis: Potential precursor for creating functionalized organic-inorganic hybrid materials with specific surface properties.
• Process Chemistry: Serves as a protected intermediate in multi-step synthetic routes, where the trimethylsilyl (TMS) group offers temporary stability.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Silane, (Estra-1,3,5(10),16-Tetraen-3-Yloxy)Trimethyl-
CAS No.	69688-27-3
Molecular Formula	C21H32OSi
Molecular Weight	328.57 g/mol
Synonyms	3-(Trimethylsilyloxy)estra-1,3,5(10),16-tetraene; Estratetraen-3-ol, trimethylsilyl ether; Trimethyl(estra-1,3,5(10),16-tetraen-3-yloxy)silane; 3-Trimethylsilyloxyestra-1,3,5(10),16-tetraene; (Estra-1,3,5(10),16-tetraen-3-yloxy)trimethylsilane; TMS ether of 3-hydroxyestra-1,3,5(10),16-tetraene
EINECS	Contact for details

Quality Control

Our high-purity Silane, (Estra-1,3,5(10),16-Tetraen-3-Yloxy)Trimethyl- is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure full traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.