Description

3,14,17β-Tris(Trimethylsiloxy)-1,3,5(10)-Estratriene is a high-purity, organosilicon-modified steroid derivative, specifically designed for advanced pharmaceutical and fine chemical synthesis. This compound is valued for its role as a key protected intermediate, enabling precise chemical transformations in the development of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for the synthesis of novel steroid-based therapeutics and high-value research compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for exploring new chemical entities and metabolic pathways in medicinal chemistry.
• Process Chemistry: Serves as a protected intermediate in scalable process development for manufacturing complex steroid derivatives.
• Bioconjugation & Probe Development: Facilitates the creation of labeled steroid probes for biochemical assays and diagnostic research due to its modifiable siloxy groups.
• Fine Chemical Synthesis: Employed in the production of high-value specialty chemicals requiring precise stereochemical control.

Basic Information

Item	Detail
Product Name	3,14,17β-Tris(Trimethylsiloxy)-1,3,5(10)-Estratriene
CAS No.	69688-23-9
Molecular Formula	C30H52O3Si3
Molecular Weight	545.0 g/mol
Synonyms	3,14,17β-Tris(trimethylsilyloxy)estra-1,3,5(10)-triene; Estra-1,3,5(10)-triene-3,14,17β-triol, tris(trimethylsilyl) ether; Tris-O-trimethylsilyl estradiol derivative; TMS-Estradiol derivative; 3,14,17β-Tri-O-TMS-estratriene; 69688-23-9; Estratriene tris(trimethylsilyl ether)
EINECS	Contact for details

Quality Control

Our 3,14,17β-Tris(Trimethylsiloxy)-1,3,5(10)-Estratriene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can compromise product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.