Description

2β-(Trimethylsiloxy)Androst-4-Ene-3,17-Dione is a key steroidal intermediate featuring a strategically protected 2β-hydroxyl group. This compound is essential for the synthesis of more complex steroid derivatives, offering a versatile building block for pharmaceutical research and development. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors for the production of active pharmaceutical ingredients (APIs) and other high-value steroid compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and hormones.
• Steroid Derivative Synthesis: Used to introduce the 2β-trimethylsiloxy functional group into more complex steroid frameworks.
• Research & Development: Serves as a valuable reference standard and building block in medicinal chemistry and process development.
• Fine Chemical Production: Employed in the manufacture of specialized, high-purity steroid compounds for various applications.

Basic Information

Item	Information
Product Name	2β-(Trimethylsiloxy)Androst-4-Ene-3,17-Dione
CAS No.	69688-13-7
Molecular Formula	C22H34O3Si
Molecular Weight	374.60 g/mol
Synonyms	2β-(Trimethylsilyloxy)androst-4-ene-3,17-dione; 2β-Hydroxyandrost-4-ene-3,17-dione 2-trimethylsilyl ether; Androst-4-ene-3,17-dione, 2β-(trimethylsiloxy)-; 2β-TMS-androstenedione; 2β-(Trimethylsiloxy)-4-androstene-3,17-dione
EINECS	Contact for details

Quality Control

Our 2β-(Trimethylsiloxy)Androst-4-Ene-3,17-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.