Description

Valine, 3-Methyl-, Ethyl Ester is a protected amino acid derivative, specifically the ethyl ester of 3-methylvaline. This compound is a crucial chiral building block in organic synthesis, valued for its role in introducing the sterically hindered 3-methylvaline moiety into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the non-proteinogenic amino acid 3-methylvaline into peptide chains.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with specific chiral configurations for enhanced activity.
• Biochemical Research: Employed in studying enzyme-substrate interactions and designing enzyme inhibitors due to its sterically demanding side chain.
• Fine Chemical Synthesis: Utilized in the asymmetric synthesis of complex natural products and specialty chemicals requiring high stereochemical purity.

Basic Information

Item	Details
Product Name	Valine, 3-Methyl-, Ethyl Ester
CAS No.	69610-03-3
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	Ethyl 3-Methylvalinate; L-3-Methylvaline Ethyl Ester; (S)-2-Amino-3-methylpentanoic Acid Ethyl Ester; 3-Methyl-L-valine Ethyl Ester; Ethyl (S)-2-amino-3-methylpentanoate; 3-Methylvaline Ethyl Ester; 2-Amino-3-methylpentanoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Valine, 3-Methyl-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.