Description

Methyl cis-3-Hydroxy-3-Phenyl-Cyclobutanecarboxylate is a high-purity, synthetically valuable cyclobutane derivative. This compound serves as a crucial chiral building block and advanced pharmaceutical intermediate for the synthesis of complex active molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring the cis-3-hydroxy-3-phenyl-cyclobutane scaffold.
• Academic & Contract Research: Employed in organic chemistry research, methodology development, and asymmetric synthesis studies.
• Material Science: Potential monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.

Basic Information

Product Name	Methyl cis-3-Hydroxy-3-Phenyl-Cyclobutanecarboxylate
CAS No.	69584-45-8
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	Methyl (1R,3S)-3-Hydroxy-3-phenylcyclobutanecarboxylate; Methyl (1S,3R)-3-Hydroxy-3-phenylcyclobutanecarboxylate; cis-Methyl 3-hydroxy-3-phenylcyclobutanecarboxylate; 3-Phenyl-3-hydroxycyclobutanecarboxylic acid methyl ester; (cis)-Methyl 3-hydroxy-3-phenylcyclobutanecarboxylate; Cyclobutanecarboxylic acid, 3-hydroxy-3-phenyl-, methyl ester, cis-; Methyl 3-hydroxy-3-phenylcyclobutane-1-carboxylate (cis)
EINECS	Contact for details

Quality Control

Our Methyl cis-3-Hydroxy-3-Phenyl-Cyclobutanecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.