Description

Dibenzyl 2-Aminopentanedioate is a protected amino acid derivative, specifically the dibenzyl ester of 2-aminopentanedioic acid (glutamic acid). This compound serves as a crucial building block in organic synthesis, offering a masked carboxylic acid and amine functionality for controlled peptide coupling and molecular construction. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), peptides, and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of peptide-based drugs and other therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected glutamic acid derivative to prevent unwanted side reactions.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Research: Employed in academic and industrial R&D for constructing complex molecular architectures requiring orthogonal protecting group strategies.
• Agrochemical Synthesis: Potential intermediate in the production of specialized agrochemicals and plant growth regulators.
• Material Science: Building block for novel polymers and dendrimers with specific functional group arrays.

Basic Information

Product Name	Dibenzyl 2-Aminopentanedioate
CAS No.	69408-26-0
Molecular Formula	C19H21NO4
Molecular Weight	327.38 g/mol
Synonyms	Dibenzyl L-Glutamate; Dibenzyl Glutamate; L-Glutamic Acid Dibenzyl Ester; (S)-2-Aminopentanedioic Acid Dibenzyl Ester; Glutamic Acid Dibenzyl Ester; DBG; Dibenzyl 2-Aminoglutarate; Benzyl (S)-2-amino-1,5-dibenzyl 1,5-dioxopentane-1,5-dioate
EINECS	Contact for details

Quality Control

Our Dibenzyl 2-Aminopentanedioate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.