Description

Mefloquine-Sulfadoxine-Pyrimethamine is a fixed-dose combination antimalarial active pharmaceutical ingredient (API). This compound is critical for the formulation of effective combination therapies that combat drug-resistant strains of malaria parasites. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antimalarial medications for global health initiatives.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antimalarial combination therapy tablets.
• Drug Formulation: Used in the development of fixed-dose combination (FDC) products to improve patient compliance and treatment efficacy.
• Clinical Research: Serves as a reference standard or raw material in pharmacological studies and clinical trials for malaria treatment.
• Public Health Programs: Essential for producing medications supplied to malaria-endemic regions through international aid and health organizations.
• Generic Drug Manufacturing: Key component for companies producing generic versions of established antimalarial therapies.

Basic Information

Product Name	Mefloquine-Sulfadoxine-Pyrimethamine
CAS No.	69191-18-0
Molecular Formula	C17H16F6N2O • C12H14N4O4S • C12H13ClN4
Molecular Weight	Contact for details
Synonyms	Mefloquine/Sulfadoxine/Pyrimethamine; Mefloquine Sulfadoxine Pyrimethamine Combination; Mefloquine-Sulfadoxine-Pyrimethamine API; MSP Combination; Antimalarial Combination API; Fansimef (related brand); Mefloquine Hydrochloride/Sulfadoxine/Pyrimethamine; Mefloquine base/Sulfadoxine/Pyrimethamine
EINECS	Contact for details

Quality Control

Our Mefloquine-Sulfadoxine-Pyrimethamine is manufactured under strict quality management systems. Each batch is tested to ensure compliance with relevant pharmacopeial standards (such as USP/EP) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing all test results, including assay, related substances, and residual solvents, is provided with every shipment to guarantee supply reliability and product consistency for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	NMT 1.0% total
Water Content (KF)	NMT 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.