Description

Butanoicacid, 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]- is a high-purity, protected butyric acid derivative featuring a tert-butyldimethylsilyl (TBDMS) ether group, serving as a crucial synthetic intermediate. This compound is valued for its role in introducing the butyric acid moiety into complex molecules while protecting the reactive hydroxyl group during multi-step synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the production of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for prodrug development and molecule functionalization.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators requiring protected acid functionalities.
• Organic Synthesis & Research: A versatile reagent for constructing complex organic molecules in academic and industrial R&D laboratories.
• Peptide & Protein Modification: Employed to introduce lipophilic butyrate groups or as a protecting group strategy in peptide chemistry.
• Flavor & Fragrance Precursor: Serves as a protected intermediate in the controlled synthesis of specific ester-based flavor and aroma compounds.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	Butanoicacid, 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-
CAS No.	69171-62-6
Molecular Formula	C10H22O3Si
Molecular Weight	218.37 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]butanoic acid; 4-(TBDMS-oxy)butyric acid; 4-(tert-Butyldimethylsiloxy)butanoic acid; γ-(tert-Butyldimethylsiloxy)butyric acid; 4-Hydroxybutyric acid TBDMS ether; TBDMS-protected 4-hydroxybutyric acid; Butanoic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 4-O-TBDMS-butanoic acid
EINECS	Contact for details

Quality Control

Our Butanoicacid, 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.