Description

Diethyl 2-Hydroxyglutarate, also known as 2-Hydroxyglutaric acid diethyl ester, is a versatile diester derivative of 2-hydroxyglutaric acid. This compound serves as a valuable chemical intermediate and building block in advanced organic synthesis, prized for its bifunctional reactivity. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds targeting metabolic pathways.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Polymer Modifier: Acts as a monomer or cross-linking agent in the synthesis of specialty polyesters and biodegradable polymers.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel compound libraries.
• Ligand and Catalyst Preparation: Useful in the synthesis of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Diethyl 2-Hydroxyglutarate
CAS No.	69134-53-8
Molecular Formula	C9H16O5
Molecular Weight	204.22 g/mol
Synonyms	2-Hydroxyglutaric Acid Diethyl Ester; Diethyl 2-Hydroxypentanedioate; Ethyl 2-Hydroxyglutarate; 2-Hydroxy-1,5-pentanedioic Acid Diethyl Ester; Diethyl α-Hydroxyglutarate; Glutaric Acid, 2-Hydroxy-, Diethyl Ester; 69134-53-8; Diethyl 2-Hydroxypentanedioate
EINECS	Contact for details

Quality Control

Every batch of Diethyl 2-Hydroxyglutarate is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.430 - 1.440
Density (20°C)	1.10 - 1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.