Description

Methyl 2-Bromobutyrate is a versatile brominated ester building block, essential for introducing the 2-bromobutyrate moiety into complex molecular frameworks. Its high reactivity, particularly in nucleophilic substitution and coupling reactions, makes it a critical intermediate for advanced organic synthesis. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents requiring specific brominated ester functionalities.
• Organic Synthesis Building Block: Employed in alkylation, esterification, and palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex organic molecules.
• Liquid Crystal & OLED Material Production: Serves as a precursor in the manufacture of brominated intermediates for electronic and display materials.
• Polymer & Resin Modification: Utilized to introduce bromine atoms into polymer chains, modifying properties like flame retardancy.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing specific ester compounds used in specialty aroma chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development and exploring new synthetic pathways in chemistry labs.

Basic Information

Product Name	Methyl 2-Bromobutyrate
CAS No.	69043-96-5
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	2-Bromobutyric Acid Methyl Ester; Methyl α-Bromobutyrate; Butanoic acid, 2-bromo-, methyl ester; Methyl 2-bromobutanoate; 2-Bromobutanoic acid methyl ester; α-Bromobutyric acid methyl ester; Methyl ester of 2-bromobutyric acid
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromobutyrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat and ignition sources. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature: 2-8°C for extended stability, though short-term storage at 15-25°C is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.450 - 1.460
Density	1.40 - 1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.