Description

5-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylidene]-1,3-Diazinane-2,4,6 -Trione is a specialized nitrogen mustard derivative with a barbituric acid core, representing a key synthetic intermediate in advanced pharmaceutical research. This compound matters for its role as a critical building block in the development of targeted chemotherapeutic agents and other biologically active molecules. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on oncology drug discovery and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential nitrogen mustard-based chemotherapeutic agents and prodrugs.
• Oncology Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of alkylating agents and developing new anti-cancer candidates.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to investigate DNA alkylation mechanisms and cellular response pathways.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex heterocyclic systems incorporating both barbiturate and mustard pharmacophores.
• API Development: Utilized in the research and early-stage development of new Active Pharmaceutical Ingredients (APIs) with targeted delivery mechanisms.

Basic Information

Product Name	5-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylidene]-1,3-Diazinane-2,4,6 -Trione
CAS No.	68961-21-7
Molecular Formula	C15H15Cl2N3O3
Molecular Weight	356.20 g/mol
Synonyms	5-[(4-[Bis(2-chloroethyl)amino]phenyl)methylene]pyrimidine-2,4,6(1H,3H,5H)-trione; 5-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylene]Barbituric Acid; 4-[Bis(2-chloroethyl)amino]benzylidenebarbituric acid; Nitrogen Mustard Barbiturate Derivative; Bis(2-chloroethyl)(4-((2,4,6-trioxotetrahydropyrimidin-5-ylidene)methyl)phenyl)amine; 68961-21-7 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our 5-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylidene]-1,3-Diazinane-2,4,6 -Trione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.