Description

4-Isoxazolecarboxylic Acid, 3-(4-Chlorophenyl)-5-Methyl-, Methyl is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate functionalized isoxazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the isoxazole ring contributes to biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry and biochemical research to study enzyme interactions and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Isoxazolecarboxylic Acid, 3-(4-Chlorophenyl)-5-Methyl-, Methyl
CAS No.	68870-58-6
Molecular Formula	C12H10ClNO3
Molecular Weight	251.67 g/mol
Synonyms	Methyl 3-(4-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate; Methyl 3-(p-chlorophenyl)-5-methylisoxazole-4-carboxylate; 3-(4-Chlorophenyl)-5-methyl-4-isoxazolecarboxylic acid methyl ester; 3-(p-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-3-(4-chlorophenyl)-5-methylisoxazole; 68870-58-6; Methyl 3-(4-chlorophenyl)-5-methyl-4-isoxazolecarboxylate
EINECS	Contact for details

Quality Control

Our 4-Isoxazolecarboxylic Acid, 3-(4-Chlorophenyl)-5-Methyl-, Methyl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.