Description

(4R)-4α-Phenyltetrahydrofuran-2-One CAS NO 68844-04-2 is a high-purity chiral lactone building block of significant interest in advanced organic synthesis. Its defined stereochemistry and functionalized structure make it a valuable precursor for creating complex, optically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Catalyst and Ligand Development: Serves as a precursor for novel chiral catalysts and ligands used in enantioselective transformations.
• Academic and R&D: Employed in research laboratories for methodological studies in organic chemistry and the exploration of new synthetic pathways.
• Material Science: Potential building block for specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	(4R)-4α-Phenyltetrahydrofuran-2-One
CAS No.	68844-04-2
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(4R)-4-Phenyl-dihydrofuran-2(3H)-one; (R)-4-Phenylbutyrolactone; (R)-4-Phenyl-γ-butyrolactone; (R)-4-Phenyl-2-oxotetrahydrofuran; (4R)-4-Phenyloxolan-2-one; (R)-4-Phenyl-γ-lactone; (R)-4-Phenylbutan-4-olide; (R)-4-Phenyltetrahydro-2-furanone
EINECS	Contact for details

Quality Control

Our (4R)-4α-Phenyltetrahydrofuran-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (by HPLC/GC), and identification. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.