Description

Phenolphthalein Diphosphate Tetrasodium Salt is a high-purity, water-soluble derivative of phenolphthalein, specifically designed as a chromogenic substrate for enzymatic assays. This compound is critical for precise biochemical detection and quantification, offering superior sensitivity and reliability in diagnostic applications. It is primarily utilized by manufacturers and research laboratories in the in-vitro diagnostic (IVD), pharmaceutical research, and life science sectors.

Application

• Primary Substrate for Alkaline Phosphatase (ALP): Used as a key chromogenic component in ELISA kits, immunoblotting, and histochemical staining for detecting ALP-labeled antibodies or probes.
• Clinical Diagnostics: Essential for automated and manual clinical chemistry analyzers to measure ALP activity in serum, a crucial marker for liver and bone disorders.
• Molecular Biology Research: Employed in nucleic acid detection systems (e.g., Southern, Northern, and Western blots) utilizing ALP-conjugated detection methods.
• Pharmaceutical Quality Control: Acts as a reagent in enzymatic assays for drug screening and the quality testing of biological products.
• Point-of-Care Testing (POCT): Formulated into dry chemistry strips and lateral flow devices for rapid, colorimetric diagnostic tests.
• Biochemical Reagent Manufacturing: Sourced by producers of high-grade reagents, buffers, and ready-to-use assay kits for global distribution.

Basic Information

Product Name	Phenolphthalein Diphosphate Tetrasodium Salt
CAS No.	68807-90-9
Molecular Formula	C20H12Na4O10P2
Molecular Weight	610.21 g/mol
Synonyms	Phenolphthalein Diphosphate Tetrasodium; Phenolphthalein Bis(phosphate) Tetrasodium Salt; 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone Diphosphate Tetrasodium Salt; Phenolphthalein Diphosphate, Tetrasodium Salt; ALP Substrate; PPP; PDP; Diagnostic Grade Phenolphthalein Phosphate; NSC 113939
EINECS	Contact for details

Quality Control

Our Phenolphthalein Diphosphate Tetrasodium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, spectrophotometric analysis for functional performance, and stringent control of moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Production adheres to ISO 13485 standards, supporting its use in regulated diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. For long-term stability, consider storage under desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Functional Test (ALP Activity)	Conforms to reference standard
pH (1% Solution)	7.0 - 9.0
Solubility (in Water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.