Description

Sodium (S)-Alpha,Alpha,4-Trimethylcyclohex-3-Ene-1-Methanolate is a chiral, non-racemic organosodium compound that serves as a versatile intermediate and reagent in advanced organic synthesis. Its value lies in its ability to act as a strong, sterically hindered base or a chiral nucleophile, enabling the stereoselective construction of complex molecular frameworks. This high-purity chemical is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• Asymmetric Synthesis: Employed as a chiral base or nucleophile in stereoselective carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediates: A critical building block for the synthesis of complex, optically active drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst and Ligand Preparation: Used in the preparation of chiral catalysts and ligands for homogeneous catalysis.
• Fine Chemical Production: Facilitates the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	Sodium (S)-Alpha,Alpha,4-Trimethylcyclohex-3-Ene-1-Methanolate
CAS No.	68797-63-7
Molecular Formula	C10H17NaO
Molecular Weight	176.23 g/mol
Synonyms	(1S)-4,4,6-Trimethyl-2-cyclohexen-1-ylmethanol, sodium salt; (S)-(-)-4,4,6-Trimethyl-2-cyclohexen-1-ylmethanol sodium derivative; Sodium (S)-(-)-4,4,6-Trimethyl-2-cyclohexen-1-methoxide; (S)-α,α,4-Trimethyl-3-cyclohexene-1-methanol, sodium salt; Sodium (S)-Perillyl Alcoholate
EINECS	Contact for details

Quality Control

Our Sodium (S)-Alpha,Alpha,4-Trimethylcyclohex-3-Ene-1-Methanolate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its hygroscopic and strong alkali nature, the material must be kept away from moisture, acids, and incompatible materials. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.